Every year, it seems we hit peak skincare ingredients. First came hyaluronic acid—once as unfamiliar as Latin, now a hydration staple. Then came the wave of niacinamide, snail mucin, retinol, and all the “-nals” and “-noids,” not to mention the incredible innovations from Japanese and Korean R&D. By 2026, we’re not just familiar with these ingredients—we know how to layer and combine them seamlessly.

With so much buzz, some ingredients fly under the radar, included in formulas but rarely in the spotlight. Beta-glucan is a perfect example—and it’s absolutely worth your attention.

What is beta-glucan?

“Beta-glucan is a polysaccharide—a type of carbohydrate—derived from sources like oats, mushrooms, and certain yeasts,” explains aesthetic doctor Dr. David Jack. “In skincare, it acts as a biological soother: it interacts with receptors on immune cells in the skin, helping to calm inflammation and support repair. Think of it as a calm, competent first responder that puts out microscopic fires before they become visible redness or irritation.”

If you like to categorize skincare ingredients, consider beta-glucan alongside other soothing stars like ectoin, ceramides, and allantoin.

Is beta-glucan good for the skin barrier?

Yes. “Beta-glucan is well-documented for its calming and barrier-supporting properties,” says consultant dermatologist Dr. Derrick Phillips. “It can be especially helpful for easily irritated or redness-prone skin, including conditions like rosacea, eczema, and contact dermatitis.”

Beta-glucan benefits the skin barrier thanks to its humectant properties. Humectants draw moisture into the skin, helping to lock in hydration and prevent water loss, which allows the skin barrier to calm down and begin repairing itself.

Is beta-glucan a good moisturizer?

Again, yes. “Beta-glucan is ideal for all skin types, but especially for dry, dehydrated skin,” says Allies Of Skin founder Nicolas Travis. It earns top marks for moisturizing not only because it draws hydration into the skin, but also because it forms a protective film to help prevent moisture loss.

“Clinically, you see plumper, less reactive skin after using beta-glucan, which is why it’s become so popular in post-procedure products and formulas for sensitive skin,” adds Dr. Jack.

What skin types or concerns is beta-glucan best suited for?

While all skin types can benefit, those with dry, dehydrated, or dull skin may notice more immediate results. Dr. Jack notes it’s particularly suited for:
– Sensitive skin
– Rosacea-prone skin
– Compromised barrier function
– Irritation from active ingredients like retinol or vitamin C

Can I use beta-glucan and retinol together?

Absolutely. Thanks to its soothing nature, beta-glucan works beautifully alongside retinoids, vitamin C, and exfoliating acids. “Its calming properties can offset some of the dryness and irritation these actives may cause,” says Dr. Phillips. “By improving skin comfort and barrier function, beta-glucan actually helps you use these ingredients more consistently with less irritation.”

Dr. Jack recommends pairing beta-glucan with hyaluronic acid for a hydration powerhouse. “Hyaluronic acid provides instant hydration, while beta-glucan strengthens resilience and moisture retention over time,” he explains. So instead of choosing between them, combine both for a short- and long-term moisture solution.

Curious about a beauty or wellness trend? We want to know! Send your questions to Vogue’s senior beauty & wellness editor.or email us at beauty@vogue.com.

Frequently Asked Questions
Of course Here is a list of helpful FAQs about BetaGlucan presented as if a skincare enthusiast is asking them

BetaGlucan in Skincare Your FAQ Guide

Beginner Definition Questions

1 What exactly is BetaGlucan
Its a powerful sugar molecule naturally found in things like oats mushrooms and yeast In skincare its a superstar hydrating and soothing ingredient that works with your skins own defenses

2 Is this a new ingredient
Not at all Its been used for years in wound healing and supplements Its popularity in mainstream skincare is soaring because people are looking for effective gentle and skinidentical actives

3 What skin types is it good for
Literally all of them Its especially fantastic for sensitive dry red or acneprone skin because its so calming but even oily and normal skin benefit from its hydration and barrier support

Benefits How It Works

4 What are the main benefits for my skin
Intense Hydration It acts like a moisture magnet holding water in the skin better than hyaluronic acid in some cases
Soothes Redness Irritation It calms skin reduces redness and helps repair a compromised skin barrier
Supports Healing It encourages skin repair making it great for calming active breakouts reducing irritation from retinol or healing after procedures
Antioxidant Protection It helps defend skin against environmental stressors like pollution

5 How does it work differently from hyaluronic acid
Think of hyaluronic acid as a water reservoir BetaGlucan is that plus a security guard It not only holds water but also binds to skin cells to reinforce your protective barrier and sends calming signals to your immune system which HA doesnt do

6 Can it help with antiaging
Yes indirectly By deeply hydrating strengthening the skin barrier and reducing chronic inflammation it helps skin look plumper smoother and more resilientkey factors in a youthful appearance

Usage Practical Tips

7 How do I use it in my routine
Its very versatile Look for it in